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SOFA Statistics – desktop GUI program focused on ease of use, learn as you go, and beautiful output.Simfit – simulation, curve fitting, statistics, and plotting.Shogun (toolbox) – open-source, large-scale machine learning toolbox that provides several SVM (Support Vector Machine) implementations (like libSVM, SVMlight) under a common framework and interfaces to Octave, MATLAB, Python, R.

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statsmodels – extends SciPy with statistical models and tests (regression, plotting, example datasets, generalized linear model (GLM), time series analysis, autoregressive–moving-average model (ARMA), vector autoregression (VAR), non-parametric statistics, ANOVA, empirical likelihood).

scikit-learn – extends SciPy with a host of machine learning models (classification, clustering, regression, etc.).

SciPy – Python library for scientific computing that contains the stats sub-package which is partly based on the venerable |STAT (a.k.a.

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Scilab – uses GPL-compatible CeCILL license.

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Salstat – menu-driven statistics software.

ROOT – an open-source C++ system for data storage, processing and analysis, developed by CERN and used to find the Higgs boson.

RStudio – GUI interface and development environment for R.

Revolution Analytics – production-grade software for the enterprise big data analytics.

Programming with Big Data in R (pbdR) – a series of R packages enhanced by SPMD parallelism for big data analysis.

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R – free implementation of the S (programming language).

PSPP – A free software alternative to IBM SPSS Statistics.

Ploticus – software for generating a variety of graphs from raw data.Perl Data Language – Scientific computing with Perl.Pandas – High-performance computing (HPC) data structures and data analysis tools for Python in Python and Cython (statsmodels, scikit-learn).Orange, a data mining, machine learning, and bioinformatics software.OpenMx – A package for structural equation modeling running in R (programming language).OpenNN – A software library written in the programming language C++ which implements neural networks, a main area of deep learning research.OpenEpi – A web-based, open-source, operating-independent series of programs for use in epidemiology and statistics based on JavaScript and HTML.Neurophysiological Biomarker Toolbox – Matlab toolbox for data-mining of neurophysiological biomarkers.Mondrian – data analysis tool using interactive statistical graphics with a link to R.mlpack – open-source library for machine learning, exploits C++ language features to provide maximum performance and flexibility while providing a simple and consistent application programming interface (API).LIBSVM – C++ support vector machine libraries.KNIME – An open source analytics platform built with Java and Eclipse using modular data pipeline workflows.JMulTi – For econometric analysis, specialised in univariate and multivariate time series analysis.Just another Gibbs sampler (JAGS) – a program for analyzing Bayesian hierarchical models using Markov chain Monte Carlo developed by Martyn Plummer.JASP – A free software alternative to IBM SPSS Statistics with additional option for Bayesian methods.intrinsic Noise Analyzer (iNA) – For analyzing intrinsic fluctuations in biochemical systems.gretl – gnu regression, econometrics and time-series library.GNU Octave – programming language very similar to MATLAB with statistical features.Fityk – nonlinear regression software (GUI and command line).Epi Info – statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC).Environment for DeveLoping KDD-Applications Supported by Index-Structures (ELKI) a software framework for developing data mining algorithms in Java.

Chronux – for neurobiological time series data.

ADMB – a software suite for non-linear statistical modeling based on C++ which uses automatic differentiation.

ADaMSoft – a generalized statistical software with data mining algorithms and methods for data management.

Gretl is an example of an open-source statistical package